Name: Gulammehdi Haji      

Theme: Myelodysplasia

 

OPTION LIST

 

A

Refractory anaemia

I

5q syndrome

B

Refarctory anaemia with an excess of blasts

J

Juvenile myelomonocytic leukaemia

C

Acute myeloid leukaemia

K

Refractory cytopenia with multilineage dysplasia

D

Myelofibrosis

L

 

E

Myelodysplastic syndrome

M

 

F

Idiopathic aplastic anaemia

N

 

G

Secondary aplastic anaemia

O

 

H

Inherited aplastic anaemia

P

 

 

 

For each scenario below, choose the most appropriate answer from the list above. Each option may be used once, more than once or not at all.

 

1.  A 34 year old man with peripheral cytopenia suffers from bleeding gums.  Peripheral blood shows 5% blast cells and bone marrow 42% blast cells.

 

 

2.  A 70 year old woman bruises easily, blood tests reveal a pancytopenic picture and karyotypic analysis is abnormal. 

 

 

3. A 20 year old man with hepatitis C complains of fatigue and breathlessness and bruises very easily.

 

 

4.  This patients blood film shows classic Pelger-Huet neutrophils and bone marrow blasts make up 15% of cells.

 

 

5.  In this case haemoglobin is normal but there is a reduction in platelets and neutrophils

 

 

 

 

ANSWERS

1. C

2. I

3. G

4. B

5. K